Zacks Investment Research lowered shares of Protagonist Therapeutics (NASDAQ:PTGX) from a strong-buy rating to a hold rating in a research note issued to investors on Thursday, January 4th.

According to Zacks, “Protagonist Therapeutics, Inc. is a clinical-stage biopharmaceutical company with a proprietary technology platform focused on discovering and developing peptide-based new chemical entities to address significant unmet medical needs. The Company’s initial lead product candidates consists of PTG-100 and PTG-200, which have the potential to transform the existing treatment paradigm for inflammatory bowel disease, a GI disease consisting primarily of ulcerative colitis and Crohn’s disease; PTG-300, an injectable hepcidin mimetic. Protagonist Therapeutics, Inc. is based in Milpitas, United States. “

A number of other equities research analysts have also commented on the company. BMO Capital Markets lowered their price target on Protagonist Therapeutics from $45.00 to $40.00 and set an outperform rating for the company in a research report on Thursday, October 19th. BidaskClub lowered Protagonist Therapeutics from a buy rating to a hold rating in a research report on Tuesday, December 12th. Finally, ValuEngine lowered Protagonist Therapeutics from a hold rating to a sell rating in a research report on Monday, September 11th. Two analysts have rated the stock with a sell rating, one has issued a hold rating and three have assigned a buy rating to the company’s stock. Protagonist Therapeutics presently has a consensus rating of Hold and an average price target of $32.50.

Shares of Protagonist Therapeutics (PTGX) traded up $0.14 during trading hours on Thursday, hitting $21.89. The stock had a trading volume of 31,070 shares, compared to its average volume of 123,027. Protagonist Therapeutics has a one year low of $8.00 and a one year high of $22.50.

Protagonist Therapeutics (NASDAQ:PTGX) last issued its earnings results on Monday, November 6th. The company reported ($0.29) earnings per share for the quarter, topping analysts’ consensus estimates of ($0.69) by $0.40. The firm had revenue of $8.78 million for the quarter.

In other news, insider David Y. Liu sold 7,000 shares of Protagonist Therapeutics stock in a transaction dated Monday, November 13th. The stock was sold at an average price of $16.97, for a total transaction of $118,790.00. The sale was disclosed in a filing with the Securities & Exchange Commission, which is accessible through the SEC website. Also, insider Dinesh V. Ph D. Patel sold 1,790 shares of Protagonist Therapeutics stock in a transaction dated Wednesday, December 20th. The shares were sold at an average price of $19.55, for a total value of $34,994.50. Following the sale, the insider now owns 192,227 shares of the company’s stock, valued at approximately $3,758,037.85. The disclosure for this sale can be found here. In the last 90 days, insiders sold 22,944 shares of company stock valued at $438,629. 15.50% of the stock is owned by corporate insiders.

Several hedge funds and other institutional investors have recently made changes to their positions in PTGX. Rhumbline Advisers purchased a new position in shares of Protagonist Therapeutics during the 2nd quarter valued at about $114,000. Bank of Montreal Can increased its stake in Protagonist Therapeutics by 1,086.0% in the 4th quarter. Bank of Montreal Can now owns 5,930 shares of the company’s stock worth $123,000 after purchasing an additional 5,430 shares during the period. Wells Fargo & Company MN increased its stake in Protagonist Therapeutics by 60.8% in the 3rd quarter. Wells Fargo & Company MN now owns 9,565 shares of the company’s stock worth $169,000 after purchasing an additional 3,617 shares during the period. Teachers Advisors LLC increased its stake in Protagonist Therapeutics by 71.4% in the 2nd quarter. Teachers Advisors LLC now owns 16,218 shares of the company’s stock worth $183,000 after purchasing an additional 6,757 shares during the period. Finally, California State Teachers Retirement System increased its stake in Protagonist Therapeutics by 8.5% in the 2nd quarter. California State Teachers Retirement System now owns 16,600 shares of the company’s stock worth $188,000 after purchasing an additional 1,300 shares during the period. 41.86% of the stock is currently owned by institutional investors.

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About Protagonist Therapeutics

Protagonist Therapeutics, Inc is a clinical-stage biopharmaceutical company with a peptide technology platform focused on discovering and developing new chemical entities (NECs) to address significant unmet medical needs. The Company’s product pipeline includes PTG-100, PTG-200 and PTG-300. Its primary focus is on developing oral peptide drugs that target biological pathways also targeted by marketed injectable antibody drugs.

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